45 Results for "

Wikstroemia retusa A. Gray

" in MedChemExpress (MCE) Product Catalog:
Products (45)

45 Results for "Wikstroemia retusa A. Gray" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-P1290
CAS No.: 121932-06-7
Synonyms: PKI-(6-22)-amide
Target:  

PKA

Research Areas:  

Neurological Disease

PKA Inhibitor Fragment (6-22) amide is a highly potent and specific competitive inhibitor of PKA, with Ki values of 1.7 nM and 1.6 nM against human and bovine PKA catalytic subunits, respectively. The IC50 of PKA Inhibitor Fragment (6-22) amide targeting bovine PKA is 8.6 nM. PKA Inhibitor Fragment (6-22) amide effectively abolishes PKA activity in mouse brain and spinal cord, and exerts in vivo efficacy via intracerebroventricular administration. PKA Inhibitor Fragment (6-22) amide significantly reverses low-dose morphine analgesic tolerance in mice and blocks photoaffinity labeling of cAMP-dependent protein kinase. PKA Inhibitor Fragment (6-22) amide can be applied to research in fields related to the mechanism of morphine analgesic tolerance and skin wound healing .
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3
3 Cited Publications
Cat. No.: HY-Y0351
CAS No.: 103-85-5
Synonyms: Phenylthiocarbamide
Research Areas:  

Others

Phenylthiourea (Phenylthiocarbamide) is an inhibitor for phenoloxidase. Phenylthiourea inhibits enzymatic oxidation of DOPA by phenoloxidase (Ki = 0.21 μM). Phenylthiourea is an effective inhibitor for tyrosinase. Phenylthiourea can lead to graying of hair in black rats due to the interference with melanin formation .
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3
3 Cited Publications
Cat. No.: HY-N7114A
CAS No.: 982-57-0
Chloramphenicol succinate sodium is a prodrug of Chloramphenicol (HY-B0239), acting as a P2Y14R inhibitor with an IC50 of 1.585 nM. Chloramphenicol succinate sodium serves as a competitive substrate and inhibitor of succinate dehydrogenase (SDH), which may account for its toxicity. Chloramphenicol succinate sodium exerts a significant inhibitory effect on colitis. Chloramphenicol succinate sodium can be used in research related to myelosuppression, gray baby syndrome, aplastic anemia, bacterial meningitis and inflammatory bowel disease .
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1
1 Cited Publications
Cat. No.: HY-119976
CAS No.: 188425-85-6
Purity:  99.29%
Boscalid is a succinate dehydrogenase (SDHI) inhibitor with antifungal activity. Boscalid binds to the ubiquinone-binding site of fungal mitochondrial complex II, blocks ATP production and aerobic respiration, exhibits good control efficacy against a variety of plant fungal diseases including gray mold, sclerotinia rot and powdery mildew, and is widely used for disease control in agriculture. Boscalid induces apoptosis, altered lipid metabolism, mitochondrial dysfunction, respiratory impairment, oxidative stress, ROS accumulation and neurodevelopmental disorders in zebrafish. Boscalid reduces foraging ability, shortens median death time and causes chronic toxicity in exposed honeybees. Boscalid also possesses genotoxicity, cytotoxicity, elevated mitochondrial superoxide levels and early-stage apoptosis .
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1
1 Cited Publications
Cat. No.: HY-17520
CAS No.: 183675-82-3
Synonyms: MTF-753
Research Areas:  

Infection

Penthiopyrad (MTF-753) is a carboxamide Fungicide. Penthiopyrad inhibits SDH. Penthiopyrad exhibits broad-spectrum antifungal activity, being effective not only against Basidiomycetes, but also against Ascomycetes and Deuteromycetes. Penthiopyrad inhibits the mycelial growth of Alternaria mali, Botrytis cinerea, Monilinia mali, Rhizoctonia solani and Sclerotinia sclerotiorum on PDA medium, with EC50 values ranging from <0.4 ppm to 0.34 ppm and MIC values ranging from 6.6 ppm to 47.9 ppm .
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Cat. No.: HY-W013571
CAS No.: 536-66-3
Synonyms: Cuminic acid; p-Isopropyl benzoic acid
4-Isopropylbenzoic acid (Cuminic acid; p-Isopropyl benzoic acid) an aromatic monoterpenoid, is isolated from the stem bark of Bridelia retusa. 4-Isopropylbenzoic acid exhibits antifungal activities. 4-Isopropylbenzoic acid is also a reversible and uncompetitive inhibitor of mushroom tyrosinase .
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Cat. No.: HY-W004263
CAS No.: 629-96-9
Synonyms: Arachidyl alcohol
1-Eicosanol (Arachidyl alcohol) is a long-chain fatty alcohol and volatile organic compound that can be isolated from the leaves of Leea indica and produced by Bacillus velezensis ZJ1. 1-Eicosanol inhibits mycelial growth of Alternaria solani and Botrytis cinerea. 1-Eicosanol is applicable to research related to tomato early blight and tomato gray mold .
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Cat. No.: HY-N9497
CAS No.: 3687-64-7
Category:  

Natural Products

Target:  

Galectin Fungal

Galactinol is a disaccharide carbohydrate serving as a galactosyl donor, which belongs to the raffinose family oligosaccharide pathway and acts as an important osmoprotectant. Galactinol not only induces disease resistance in plants against fungal and bacterial pathogens, but also significantly enhances plant tolerance to abiotic stresses such as drought, high salinity, low temperature and oxidative damage. In addition, Galactinol has the ability to scavenge hydroxyl radicals, can act as a signaling component for root colonization-induced systemic resistance, and is positively correlated with seed longevity in various crops, making it a potential biomarker for evaluating seed vigor. Therefore, Galactinol can be used in the research of various plant diseases including fungal leaf spot, bacterial angular leaf spot, gray mold and soft rot .
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Cat. No.: HY-N6784
CAS No.: 11050-94-5
Oligomycin B is an antibiotic that acts as a non-selective inhibitor of ATP Synthase. Oligomycin B increases mitochondrial membrane potential. Oligomycin B induces apoptosis and necrosis. Oligomycin B impairs the motility of Plasmopara viticola zoospores and induces their lysis. Oligomycin B inhibits Magnaporthe oryzae (wheat blast fungus) and suppresses the development of wheat blast. Oligomycin B reduces hyphal growth and spore germination of Botrytis cinerea, and protects Arabidopsis thaliana against Botrytis cinerea infection. Oligomycin B exacerbates cytotoxic brain edema in rats with cerebral cortical contusion, increases intracranial pressure and brain water content, and aggravates mitochondrial damage in these rats. Oligomycin B is used in studies related to grape downy mildew, traumatic brain injury, wheat blast, and gray mold .
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Cat. No.: HY-113248
CAS No.: 621-44-3
Purity:  ≥98.0%
3-Nitro-L-tyrosine serves as a biomarker of oxidative stress. 3-Nitro-L-tyrosine attenuates the pressor and vasoconstrictive effects of angiotensin II by inhibiting the α1-adrenergic receptor-mediated signaling pathway, and participates in hemodynamic regulation under pathological conditions such as inflammation and ischemia. 3-Nitro-L-tyrosine can be used in studies related to atherosclerosis, ischemia-reperfusion and sepsis .
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Cat. No.: HY-P5247
Synonyms: PTP20
Palmitoyl tetrapeptide-20 (PTP20) is a biomimetic peptide agonist of α-MSH. Palmitoyl tetrapeptide-20 promotes hair pigmentation and delays hair graying by activating the MC1-R pathway (AC50: 0.16 nM), enhancing catalase activity to reduce H2O2 accumulation, and upregulating SIRT1 activity. Palmitoyl tetrapeptide-20 can be used in research on preventing hair loss and improving hair graying .
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Cat. No.: HY-P10447
CAS No.: 103651-09-8
Synonyms: Fengycin IX; SNA-60-367-3
Target:  

Phospholipase Fungal

Research Areas:  

Infection

Plipastatin A1 (Fengycin IX; SNA-60-367-3) is a lipopeptide with phospholipase A2 inhibitory activity. Plipastatin A1 inhibits conidial germination of Botrytis cinerea in vitro and reduces the incidence of gray mold on tomato leaves. Plipastatin A1 is applicable to research related to gray mold [1][2].
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Cat. No.: HY-W775091
CAS No.: 875915-78-9
Synonyms: IKF-5411
Research Areas:  

Infection

Isofetamid (IKF-5411) is a succinate dehydrogenase inhibitor and a fungicide. Isofetamid exhibits good control effects against various fungal diseases such as gray mold, white mold, and powdery mildew. Isofetamid is promising for research of plant fungal diseases .
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Cat. No.: HY-P5220
CAS No.: 448944-47-6
Synonyms: Melitane
Target:  

Melanocortin Receptor

Research Areas:  

Others

Acetyl hexapeptide-1 (Melitane) is a biomimetic peptide that mimics the activity of α-melanocyte-stimulating hormone (α-MSH). Acetyl hexapeptide-1 regulates muscle contraction, thereby reducing facial expression lines. Acetyl hexapeptide-1 is one of the components of anti-aging skincare serums targeting dynamic wrinkles. Acetyl hexapeptide-1 can be used in research related to mild photoaged facial skin and premature gray hair .
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Cat. No.: HY-P5220A
CAS No.: 2828433-36-7
Synonyms: Melitane acetate
Target:  

Melanocortin Receptor

Research Areas:  

Others

Acetyl hexapeptide-1 (Melitane) acetate is a biomimetic peptide that mimics the activity of α-melanocyte-stimulating hormone (α-MSH). Acetyl hexapeptide-1 acetate can regulate muscle contraction, thereby reducing facial expression lines. Acetyl hexapeptide-1 acetate is one of the components of anti-aging skin care essences targeting dynamic wrinkles. Acetyl hexapeptide-1 acetate can be used in studies related to mild photo-aged facial skin and premature graying of hair .
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Cat. No.: HY-N2558
CAS No.: 19668-69-0
Murrayone is a coumarin compound with antifungal and antiplatelet activities. Murrayone disrupts fungal redox homeostasis, impairs cell membrane integrity, inhibits sporulation, spore germination and hyphal growth, and causes morphological damage to fungal cells. Murrayone reduces the disease severity of blueberry fruits infected with Botrytis cinerea. Murrayone can be used in studies related to fungal infections and vascular diseases .
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Cat. No.: HY-N8736
CAS No.: 28593-90-0
Eicosanyl (E)-caffeate is a sesquiterpenoid isolated from the root of Wikstroemia scytophylla .
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Cat. No.: HY-P5247A
Synonyms: PTP20 TFA
Palmitoyl tetrapeptide-20 (PTP20) TFA is a biomimetic peptide agonist of α-MSH. Palmitoyl tetrapeptide-20 TFA promotes hair pigmentation and delays hair graying by activating the MC1-R pathway (AC50: 0.16 nM), enhancing catalase activity to reduce H2O2 accumulation, and upregulating SIRT1 activity. Palmitoyl tetrapeptide-20 TFA can be used in research on preventing hair loss and improving hair graying .
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Cat. No.: HY-135258
CAS No.: 1217474-91-3
Purity:  ≥98.0%
Target:  

Galectin Fungal

Research Areas:  

Others

Galactinol dihydrate is a disaccharide carbohydrate serving as a galactosyl donor, which belongs to the raffinose family oligosaccharide pathway and acts as an important osmoprotectant. Galactinol dihydrate not only induces disease resistance in plants against fungal and bacterial pathogens, but also significantly enhances plant tolerance to abiotic stresses such as drought, high salinity, low temperature and oxidative damage. In addition, Galactinol dihydrate has the ability to scavenge hydroxyl radicals, can act as a signaling component for root colonization-induced systemic resistance, and is positively correlated with seed longevity in various crops, making it a potential biomarker for evaluating seed vigor. Therefore, Galactinol dihydrate can be used in the research of various plant diseases including fungal leaf spot, bacterial angular leaf spot, gray mold and soft rot .
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Cat. No.: HY-160052
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

IL-6 aptamer sodium is an aptamer that specifically binds to IL-6, and can serve as a biological recognition receptor for high-sensitivity detection. IL-6 aptamer sodium enables label-free specific detection through changes in electrical signals of carbon nanotube microarrays or alterations in capacitive impedance on the surface of gold sensors. IL-6 aptamer sodium still maintains high selectivity even below the gray zone threshold for cancer diagnosis, and shows no significant non-specific binding to bovine serum albumin. IL-6 aptamer sodium can form an ordered self-assembled monolayer with 6-mercapto-1-hexanol on gold surfaces, making it suitable for reagent-free capacitive impedance biosensing platforms. IL-6 aptamer sodium is widely used in research related to fields such as cancer, inflammatory diseases, myeloma, liver cancer and glioma .
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